EFFECT OF DRIVING PRESSURE-GUIDED INDIVIDUALISED POSITIVE END-EXPIRATORY PRESSURE ON POSTOPERATIVE ATELECTASIS IN PATIENTS WITH MORBID OBESITY: STUDY PROTOCOL OF A RANDOMISED CONTROLLED TRIAL

Effect of driving pressure-guided individualised positive end-expiratory pressure on postoperative atelectasis in patients with morbid obesity: study protocol of a randomised controlled trial

Introduction Atelectasis is a common postoperative complication in patients with obesity, contributing to respiratory insufficiency, pneumonia and poor clinical outcomes.Studies have shown that driving pressure (DP)-guided individualised positive end-expiratory pressure can improve respiratory mechanics and oxygenation, while also reducing the inci

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Gene expression regulation by retinoic acid

Over the last quarter century, more than 532 genes have been put forward as regulatory targets of retinoic acid.In some cases this control is direct, driven by a liganded heterodimer of retinoid receptors bound to a Hoodie DNA response element; in others, it is indirect, reflecting the actions of intermediate transcription factors, non-classical as

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